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Index > Protein center > Hcn4(Gene name) > Mouse
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  • Hcn4 (Gene name),
  • Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Protein name ),  HCN4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Hcn4(Bcng3);
    Protein name:
    Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4;
    Alternative:
    Brain cyclic nucleotide-gated channel 3(BCNG-3);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits.
    Function:
    Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) and in neurons (Ih). Activated by cAMP (By similarity). May mediate responses to sour stimuli.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1186
    Sequence:
    50:
    MDKLPPSMRK | RLYSLPQQVG | AKAWIMDEEE | DGEEEGAGGR | QDPSRRSIRL | 
    100:
    RPLPSPSPSV | AAGCSESRGA | ALGATESEGP | GRSAGKSSTN | GDCRRFRGSL | 
    150:
    ASLGSRGGGS | GGAGGGSSLG | HLHDSAEERR | LIAAEGDASP | GEDRTPPGLA | 
    200:
    TEPERPATAA | QPAASPPPQQ | PPQPASASCE | QPSADTAIKV | EGGAAAIDHI | 
    250:
    LPEAEVRLGQ | SGFMQRQFGA | MLQPGVNKFS | LRMFGSQKAV | EREQERVKSA | 
    300:
    GFWIIHPYSD | FRFYWDLTML | LLMVGNLIII | PVGITFFKDE | NTTPWIVFNV | 
    350:
    VSDTFFLIDL | VLNFRTGIVV | EDNTEIILDP | QRIKMKYLKS | WFVVDFISSI | 
    400:
    PVEYIFLIVE | TRIDSEVYKT | ARAVRIVRFT | KILSLLRLLR | LSRLIRYIHQ | 
    450:
    WEEIFHMTYD | LASAVVRIVN | LIGMMLLLCH | WDGCLQFLVP | MLQDFPHDCW | 
    500:
    VSINGMVNNS | WGKQYSYALF | KAMSHMLCIG | YGRQAPVGMS | DVWLTMLSMI | 
    550:
    VGATCYAMFI | GHATALIQSL | DSSRRQYQEK | YKQVEQYMSF | HKLPPDTRQR | 
    600:
    IHDYYEHRYQ | GKMFDEESIL | GELSEPLREE | IINFNCRKLV | ASMPLFANAD | 
    650:
    PNFVTSMLTK | LRFEVFQPGD | YIIREGTIGK | KMYFIQHGVV | SVLTKGNKET | 
    700:
    RLADGSYFGE | ICLLTRGRRT | ASVRADTYCR | LYSLSVDNFN | EVLEEYPMMR | 
    750:
    KKNSILLHKV | QHDLNSGVFN | YQENEIIQQI | VRHDREMAHC | AHRVQAAASA | 
    800:
    TPTPTPVIWT | PLIQAPLQAA | AATTSVAIAL | THHPRLPAAI | FRPPPGPGLG | 
    850:
    NLGAGQTPRH | PRRLQSLIPS | ALGSASPASS | PSQVDTPSSS | SFHIQQLAGF | 
    900:
    SAPPGLSPLL | PSSSSSPPPG | ACGSPPAPTP | STSTAAAAST | TGFGHFHKAL | 
    950:
    GGSLSSSDSP | LLTPLQPGAR | SPQAAQPPPP | LPGARGGLGL | LEHFLPPPPS | 
    1000:
    SRSPSSSPGQ | LGQPPGELSL | GLAAGPSSTP | ETPPRPERPS | FMAGASGGAS | 
    1050:
    PVAFTPRGGL | SPPGHSPGPP | RTFPSAPPRA | SGSHGSLLLP | PASSPPPPQV | 
    1100:
    PQRRGTPPLT | PGRLTQDLKL | ISASQPALPQ | DGAQTLRRAS | PHSSGESVAA | 
    1150:
    FSLYPRAGGG | SGSSGGLGPP | GRPYGAIPGQ | HVTLPRKTSS | GSLPPPLSLF | 
    1186:
    GARAASSGGP | PLTTAAPQRE | PGARSEPVRS | KLPSNL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Cat.:
    E13654h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Cat.:
    E13654r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Cat.:
    E13654m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Cat.:
    U13654h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Cat.:
    U13654m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
    Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

    R&D Technical Data


     

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "Identification of a gene encoding a hyperpolarization-activated 'pacemaker' channel of brain."
      Santoro B. , Liu D.T. , Yao H. , Bartsch D. , Kandel E.R. , Siegelbaum S.A. , Tibbs G.R.
      Cell93:717-729(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 179-684
      tissue: Brain.
    3. 3.
      "Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli."
      Stevens D.R. , Seifert R. , Bufe B. , Mueller F. , Kremmer E. , Gauss R. , Meyerhof W. , Kaupp U.B. , Lindemann B.
      Nature413:631-635(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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