Protein name:
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 ;
Alternative:
Brain cyclic nucleotide-gated channel 3 (BCNG-3) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming subunits.
Function:
Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. May contribute to the native pacemaker currents in heart (If) and in neurons (Ih). Activated by cAMP (By similarity). May mediate responses to sour stimuli.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MDKLPPSMRK | RLYSLPQQVG | AKAWIMDEEE | DGEEEGAGGR | QDPSRRSIRL |
100:
RPLPSPSPSV | AAGCSESRGA | ALGATESEGP | GRSAGKSSTN | GDCRRFRGSL |
150:
ASLGSRGGGS | GGAGGGSSLG | HLHDSAEERR | LIAAEGDASP | GEDRTPPGLA |
200:
TEPERPATAA | QPAASPPPQQ | PPQPASASCE | QPSADTAIKV | EGGAAAIDHI |
250:
LPEAEVRLGQ | SGFMQRQFGA | MLQPGVNKFS | LRMFGSQKAV | EREQERVKSA |
300:
GFWIIHPYSD | FRFYWDLTML | LLMVGNLIII | PVGITFFKDE | NTTPWIVFNV |
350:
VSDTFFLIDL | VLNFRTGIVV | EDNTEIILDP | QRIKMKYLKS | WFVVDFISSI |
400:
PVEYIFLIVE | TRIDSEVYKT | ARAVRIVRFT | KILSLLRLLR | LSRLIRYIHQ |
450:
WEEIFHMTYD | LASAVVRIVN | LIGMMLLLCH | WDGCLQFLVP | MLQDFPHDCW |
500:
VSINGMVNNS | WGKQYSYALF | KAMSHMLCIG | YGRQAPVGMS | DVWLTMLSMI |
550:
VGATCYAMFI | GHATALIQSL | DSSRRQYQEK | YKQVEQYMSF | HKLPPDTRQR |
600:
IHDYYEHRYQ | GKMFDEESIL | GELSEPLREE | IINFNCRKLV | ASMPLFANAD |
650:
PNFVTSMLTK | LRFEVFQPGD | YIIREGTIGK | KMYFIQHGVV | SVLTKGNKET |
700:
RLADGSYFGE | ICLLTRGRRT | ASVRADTYCR | LYSLSVDNFN | EVLEEYPMMR |
750:
KKNSILLHKV | QHDLNSGVFN | YQENEIIQQI | VRHDREMAHC | AHRVQAAASA |
800:
TPTPTPVIWT | PLIQAPLQAA | AATTSVAIAL | THHPRLPAAI | FRPPPGPGLG |
850:
NLGAGQTPRH | PRRLQSLIPS | ALGSASPASS | PSQVDTPSSS | SFHIQQLAGF |
900:
SAPPGLSPLL | PSSSSSPPPG | ACGSPPAPTP | STSTAAAAST | TGFGHFHKAL |
950:
GGSLSSSDSP | LLTPLQPGAR | SPQAAQPPPP | LPGARGGLGL | LEHFLPPPPS |
1000:
SRSPSSSPGQ | LGQPPGELSL | GLAAGPSSTP | ETPPRPERPS | FMAGASGGAS |
1050:
PVAFTPRGGL | SPPGHSPGPP | RTFPSAPPRA | SGSHGSLLLP | PASSPPPPQV |
1100:
PQRRGTPPLT | PGRLTQDLKL | ISASQPALPQ | DGAQTLRRAS | PHSSGESVAA |
1150:
FSLYPRAGGG | SGSSGGLGPP | GRPYGAIPGQ | HVTLPRKTSS | GSLPPPLSLF |
1186:
GARAASSGGP | PLTTAAPQRE | PGARSEPVRS | KLPSNL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Rabbit
ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
ELISA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
CLIA Kit for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Polyclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Monoclonal Antibody for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Protein for Mouse Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 179-684
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY